Publications
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CARTISTEM | 2024-02-09 Allogeneic umbilical cord blood‑derived mesenchymal stem cell implantation versus microdrilling combined with high tibial osteotomy for cartilage regeneration
CARTISTEM implantation combined with HTO was more effective than microdrilling for patient-reported outcomes and cartilage regeneration in knee osteoarthritis.· Issue information | Sci Rep. 2024 Feb 9;14(1):3333. doi: 10.1038/s41598-024-53598-9. · Co-author | Se‑Han Jung, Bum‑Joon Nam, Chong‑Hyuk Choi, Sungjun Kim, Min Jung, Kwangho Chung, Jisoo Park, Youngsu Jung & Sung‑Hwan Kim |
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CARTISTEM | 2023-07-17 Dry Arthroscopic Cartilage Repair of the Knee Joint Using Umbilical Cord Mesenchymal Stem Cells: Kelly Clamp Technique
Arthroscopic CARTISTEM implantation using a Kelly clamp is an easier and more effective method.· Issue information | Arthrosc Tech. 2023 Jul 17;12(8):e1355-e1359. doi: 10.1016/j.eats.2023.04.004. · Co-author | Tae Jin Lee, Chan Dong Jeong, Tae Hoon Lee |
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CARTISTEM | 2023-04-24 Clinical and Magnetic Resonance Imaging Outcomes After Human Cord Blood–Derived Mesenchymal Stem Cell Implantation for Chondral Defects of the Knee
Clinical outcomes improved significantly at short-term follow-up after CARTISTEM implantation for chondral defects of the knee.· Issue information | Orthop J Sports Med. 2023 Apr 24;11(4):23259671231158391. doi: 10.1177/23259671231158391. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Byung-Hun Hwangbo, Bong-Seok Yang, Brian N. Victoroff, and Nam-Hong Choi |
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CARTISTEM | 2023-03-22 Bone Marrow Aspirate Concentrate versus Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells for Combined Cartilage Regeneration Procedure in Patients Undergoing High Tibial Osteotomy: A Systematic Review and Meta-Analysis
Both BMAC and CARTISTEM with HTO improved clinical outcomes in varus knee OA patients, but CARTISTEM were more effective in articular cartilage regeneration than BMAC augmentation.· Issue information | Medicina (Kaunas). 2023 Mar 22;59(3):634.doi: 10.3390/medicina59030634. · Co-author | Dojoon Park, Youn Ho Choi, Se Hyun Kang, Hae Seok Koh, Yong In |
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CARTISTEM | 2023-03-14 Safety and effectiveness of arthroscopic-assisted implantation of allogenic umbilical cord blood-derived mesenchymal stem cells
For individuals with Osteoarthritis of the knee, chondroplasty with CARTISTEM during medial owHTO can significantly improve the radiological and clinical outcomes.· Issue information | Arthroscopy and Orthopedic Sports Medicine 10(1):28-33.doi: 10.14517/aosm23001. · Co-author | Dong Hyuk Cha, Dong Hwi Kim, Jeong Min Kook |
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CARTISTEM | 2023-01-11 Allogeneic Umbilical Cord-Blood-Derived Mesenchymal Stem Cells and Hyaluronate Composite Combined with High Tibial Osteotomy for Medial Knee Osteoarthritis with Full-Thickness Cartilage Defects
CARTISTEM-HA composite implantation combined with HTO would be a good therapeutic option for patients with knee OA and full-thickness cartilage defects.· Issue information | Medicina (Kaunas). 2023 Jan 11;59(1):148. doi: 10.3390/medicina59010148. · Co-author | Yong-Beom Park, Han-Jun Lee, Hyun-Cheul Nam and Jung-Gwan Park |
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CARTISTEM | 2022-12-06 Repair of a large patellar cartilage defect using human umbilical cord blood-derived mesenchymal stem cells: A case report
CARTISTEM implantation may be a useful treatment option for the repair of large patellar cartilage defects.· Issue information | World J Clin Cases. 2022 Dec 6;10(34):12665-12670. doi: 10.12998/wjcc.v10.i34.12665. · Co-author | Jun-Seob Song, Ki-Taek Hong, Ki Jeon Song, Seok Jung Kim |
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CARTISTEM | 2022-09-22 Cost Effectiveness of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Patients with Knee Osteoarthritis
CARTISTEM was cost effective compared with microfracture in patients with knee OA.· Issue information | Appl Health Econ Health Policy. 2022 Sep 22. doi: 10.1007/s40258-022-00762-9. · Co-author | Kangho Suh, Brian J Cole, Andreas Gomoll, Seung-Mi Lee, Hangseok Choi, Chul-Won Ha, Hong Chul Lim, Myung Ku Kim, Gwi-Yeom Ha, Dong-Churl Suh |
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CARTISTEM | 2022-09-09 Cartilage Regeneration in Osteoarthritic Patients by a Composite of Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronate Hydrogel: Results from a Clinical Trial for Safety and Proof-of-Concept with 7 Years of Extended Follow-Up
In the Phase 1/2a clinical trial, CARTISTEM implantation showed safety of treatment and effective regeneration of durable articular cartilage in osteoarthritic knees with 7 years of extended follow-up.· Issue information | Stem Cells Trans Med. 2017 Feb;6(2):613-621. doi: 10.5966/sctm.2016-0157. · Co-author | Yong-Beom Park, Chul-Won Ha, Choong-Hee Lee, Young Cheol Yoon, Yong Geun Park |
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Stem Cells | 2022-04-18 HLA-A2 Promotes the Therapeutic Effect of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Hyperoxic Lung Injury
HLA-A2 in hUCB-MSCs is a major factor that enhances therapeutic effect in hyperoxic lung injury and inflammatory conditions.· Issue information | Bioengineering (Basel). 2022 Apr;9(4):177. doi: 10.3390/bioengineering9040177. · Co-author | Jihye Kwak, Wankyu Choi, Yunkyung Bae, Miyeon Kim, Soojin Choi, Wonil Oh, Hye Jin Jin |