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Downregulation of Melanoma Cell Adhesion Molecule(MCAM/CD146) Accelerates Cellular Senescence in Human Umbilical Cord Blood-De

Stem Cells
Date
2016-03-03 17:25
Views
12
Issue information : Stem Cells Transl Med. 2016 Apr;5(4):427-39.

Co-author : Hye Jin Jin, Ji Hye Kwon, Miyeon Kim, Yun Kyung Bae, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Hong Bae Jeon


This study provides strong evidence that CD146 is a novel and useful marker for predicting senescence in human UCB-MSCs, and CD146 can potentially be applied in quality-control assessments of human UCB-MSC-based therapy.
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