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CARTISTEM | 2021-01-25 Allogenic umbilical cord blood-derived mesenchymal stromal cell implantation was superior to bone marrow aspirate concentrate augmentation for cartilage regeneration despite similar clinical outcomes
CARTISTEM was more effective than BMAC augmentation for articular cartilage regeneration in high tibial osteotomy (HTO) for medial compartmental knee osteoarthritis.· Issue information | Knee Surg Sports Traumatol Arthrosc. 2022 Jan;30(1):208-218. doi: 10.1007/s00167-021-06450-w. · Co-author | Hong‑Yeol Yang, Eun‑Kyoo Song, Sung‑Ju Kang, Woo‑Kyoung Kwak, Joon‑Kyoo Kang, Jong‑Keun Seon |
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CARTISTEM | 2021-01-12 Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cell Implantation Versus Microfracture for Large, Full-Thickness Cartilage Defects in Older Patients: A Multicenter Randomized Clinical Trial and Extended 5-Year Clinical Follow-up
In the Phase 3 clinical trial, CARTISTEM implantation showed more durable improvement of pain and function up to 5 years compared with microfracture in patients with cartilage defects with or without osteoarthritis.· Issue information | Orthop J Sports Med. 2021 Jan 12;9(1):2325967120973052. doi: 10.1177/2325967120973052. · Co-author | Hong-Chul Lim, Yong-Beom Park, Chul-Won Ha, Brian J Cole, Beom-Koo Lee, Hwa-Jae Jeong, Myung-Ku Kim, Seong-Il Bin, Chong-Hyuk Choi, Choong Hyeok Choi, Jae-Doo Yoo, Cartistem Research Group; Jung-Ro Yoon, Jun-Young Chung |
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CARTISTEM | 2020-10-17 Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results
CARTISTEM implantation combined with HTO for medial knee osteoarthritis was safe and showed cartilage status improvement.· Issue information | Int Orthop. 2021 Feb;45(2):481-488. doi: 10.1007/s00264-020-04852-y. · Co-author | Young-Woo Chung, Hong-Yeol Yang, Sung-Ju Kang, Eun-Kyoo Song, Jong-Keun Seon |
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CARTISTEM | 2020-07-27 Comparison of Bone Marrow Aspirate Concentrate and Allogenic Human Umbilical Cord Blood Derived Mesenchymal Stem Cell Implantation on Chondral Defect of Knee: Assessment of Clinical and Magnetic Resonance Imaging Outcomes at 2-Year Follow-Up
Implantation of BMAC or CARTISTEM is safe and effective for repairing cartilage lesion on Chondral Defect of Knee with 2 years follow-up.· Issue information | Cell Transplant. 2020 Jan-Dec;29:1-10. doi: 10.1177/0963689720943581. · Co-author | Dong Jin Ryu, Yoon Sang Jeon, Jun Sung Park, Gi Cheol Bae, Jeong-Seok Kim, Myung Ku Kim |
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CARTISTEM | 2020-06-26 High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration
Implantation of CARTISTEM with concomitant HTO is an effective treatment for improving cartilage regeneration in patients with medial compartment osteoarthritis and varus deformity.· Issue information | World J Stem Cells. 2020 Jun 26;12(6):514-526. doi: 10.4252/wjsc.v12.i6.514. · Co-author | Jun-Seob Song, Ki-Taek Hong, Chae-Gwan Kong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Young Ju Kim, Ki Bong Chang, Seok Jung Kim |
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CARTISTEM | 2020-01-24 Human umbilical cord blood-derived mesenchymal stem cell implantation for osteoarthritis of the knee
CARTISTEM implantation regenerated cartilage and showed satisfactory clinical outcomes in patients older than 60 years who had Medial Compartment Osteoarthritis of Knee.· Issue information | Arch Orthop Trauma Surg. 2020 Apr;140(4):503-509. doi: 10.1007/s00402-020-03349-y. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Han-Soo Park , Nam-Hong Choi |
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CARTISTEM | 2020-01-14 Implantation of allogenic umbilical cord blood-derived mesenchymal stem cells improves knee osteoarthritis outcomes: Two-year follow-up
Implantation of CARTISTEM showed effective clinical outcome for treating knee osteoarthritis based on a follow-up lasting a minimum of 2 years.· Issue information | Regen Ther. 2020 Jan 14;14:32-39. doi: 10.1016/j.reth.2019.10.003. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Sang Heon Lee, Yoon Joo Cho, Seok Jung Kim |
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CARTISTEM | 2019-08-20 Cartilage regeneration in osteoarthritic knees treated with distal femoral osteotomy and intralesional implantation of allogenic human umbilical cord blood-derived mesenchymal stem cells: A report of two cases
CARTISTEM implantation combined with DFO showed cartilage regeneration and improving clinical outcomes in two patients with valgus deformity who had lateral compartment osteoarthritis.· Issue information | Knee. 2019 Dec;26(6):1445-1450. doi: 10.1016/j.knee.2019.07.017. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, You Seung Chun, Seok Jung Kim |
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CARTISTEM | 2019-04-01 Allogenic umbilical cord blood-derived mesenchymal stem cells implantation for the treatment of juvenile osteochondritis dissecans of the knee
CARTISTEM implantation showed cartilage regeneration and improving clinical outcomes in two patients with juvenile osteochondritis dissecans of the knee at one year follow-up.· Issue information | J Clin Orthop Trauma. 2019 Oct;10(Suppl 1):S20-S25. doi: 10.1016/j.jcot.2019.03.025. · Co-author | Jun-Seob Song, Ki-Taek Hong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Yoo-Chang Kim, Asode Ananthram Shetty, Seok Jung Kim |
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CARTISTEM | 2017-02-02 Restoration of a large osteochondral defect of the knee using a composite of umbilical cord blood-derived mesenchymal stem cells and hyaluronic acid hydrogel: a case report with a 5-year follow-up
CARTISTEM implantation showed cartilage regeneration and improving clinical outcomes in one patient for large osteochondral defects of the knee at 5 years follow-up.· Issue information | BMC Musculoskelet Disord. 2017 Feb 2;18(1):59-68. doi: 10.1186/s12891-017-1422-7. · Co-author | Yong-Beom Park, Chul-Won Ha, Choong-Hee Lee, Yong-Geun Park |