Publications

Modeling and Staging of Osteoarthritis Progression Using Serial CT Imaging and Arthroscopy

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Date
2018-08-06 17:33
Views
917
Issue information : Cartilage. 2018 Aug 6:1947603518789997. doi: 10.1177/1947603518789997

Co-author : Candace Flynn, Mark Hurtig, Emma Lamoure, Erin Cummins, Valeria Roati, Mark Lowerison, Sang Young Jeong, Wonil Oh, Alex Zur Linden


This study presents an animal model of degenerative arthritis similar to humans in which the meniscal release method can be used to induce degenerative arthritis in sheep and then, the degree of cartilage damage can be checked with CT images and arthroscopy without the sacrifice of the object to determine when to administer the therapeutic agent.