Issue information : Stem Cells Dev. 2015 Oct 15;24(20):2378-90. doi: 10.1089/scd.2014.0487. Epub 2015 Aug 19.
Co-author : Dong Hyun Kim, Dahm Lee, Eun Hyuk Chang, Ji Hyun Kim, Jung Won Hwang, Ju-Yeon Kim, Jae Won Kyung, Sung Hyun Kim, Jeong Su Oh, Sang Mi Shim, Duk Lyul Na, Wonil Oh, Jong Wook Chang
Link : https://www.ncbi.nlm.nih.gov/pubmed/26154268
In this study, we elucidated that the effectiveness to repeatedly administrated hUCB-MSCs through the CSF route as well as the promotion of hippocampal neurogenesis and synaptic activity by the GDF-15 secreted from hUCB-MSCs in Alzheimer's disease model.
