Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunctio
Stem Cells
Date
2018-01-10 17:30
Views
903
Issue information : Sci Rep. 2018 Jan 10;8(1):354. doi: 10.1038/s41598-017-18542-0.
Co-author : Dong Hyun Kim, Hoon Lim, Dahm Lee, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Jeong Soo Oh, Hyun Ho Hwang, Hong Bae Jeon
Link : https://www.ncbi.nlm.nih.gov/pubmed/29321508
This study shows that TSP-1, a secretory protein of umbilical cord blood-derived mesenchymal stem cells, can restore nerve cell synapse dysfunction in Alzheimer-type dementia.