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Thrombospondin-1 secreted by human umbilical cord blood-derived mesenchymal stem cells rescues neurons from synaptic dysfunctio

NEUROSTEM
Date
2018-01-10 17:30
Views
13
Issue information : Sci Rep. 2018 Jan 10;8(1):354. doi: 10.1038/s41598-017-18542-0.

Co-author : Dong Hyun Kim, Hoon Lim, Dahm Lee, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Jeong Soo Oh, Hyun Ho Hwang, Hong Bae Jeon


This study shows that TSP-1, a secretory protein of umbilical cord blood-derived mesenchymal stem cells, can restore nerve cell synapse dysfunction in Alzheimer-type dementia.
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