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Thrombospondin-2 secreted by human umbilical cord blood-derived mesenchymal stem cells promotes chondrogenic differentiation.

CARTISTEM
Date
2013-10-01 17:22
Views
11
Issue information : Stem Cells. 2013 Oct;31(10):2136-48.

Co-author : Jeong SY, Kim DH, Ha J, Jin HJ, Kwon SJ, Chang JW, Choi SJ, Oh W, Yang YS, Kim G, Kim JS, Yoon JR, Cho DH, Jeon HB.


Although therapeutic effect of mesenchymal stem cells on cartilage disorders is well known, a lot of studies are being progressed on its mechanism. In this study, a specific protein (TSP-2) expressed by cord blood mesenchymal cells by joint fluid component was identified and the regeneration mechanism of injured cartilage was determined by secretion of this protein.
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