Issue information : Stem Cells. 2013 Oct;31(10):2136-48.
Co-author : Jeong SY, Kim DH, Ha J, Jin HJ, Kwon SJ, Chang JW, Choi SJ, Oh W, Yang YS, Kim G, Kim JS, Yoon JR, Cho DH, Jeon HB.
Link : https://www.ncbi.nlm.nih.gov/pubmed/23843355
Although therapeutic effect of mesenchymal stem cells on cartilage disorders is well known, a lot of studies are being progressed on its mechanism. In this study, a specific protein (TSP-2) expressed by cord blood mesenchymal cells by joint fluid component was identified and the regeneration mechanism of injured cartilage was determined by secretion of this protein.