Cryopreserved Cord Blood Progenitors and Their Cell Adhesion Molecules Are Increased by Coculture With Osteoblasts and Parathyr

Cord Blood
2013-08-01 17:21
Issue information : J Pediatr Hematol Oncol. 2013. Aug;35(6):e229-e233.

Co-author : Yun Kyung Jang, Miyeon Kim, Hye Jin Jin,Soo Jin Choi, Wonil Oh, and Young-Ho Lee

Despite the cord blood(CB) cells induces lower immunogenicity, CB transplantation is also associated with delayed neutrophil and platelet recovery relative to bone marrow transplantation. This suggests a possibility to increase the engraftment of hematopoietic cells in CB by increasing the abundances of primitive cells bearing adhesion molecules in the presence of hPTH.