NEUROSTEM®
Treatment of Alzheimer’s Disease
NEUROSTEM® an allogeneic umbilical cord blood-derived mesenchymal stem cell product, is under development for the treatment of Alzheimer’s Disease. Phase 2a clinical trial has been completed as of December 2019 after successfully completing the Phase 1 clinical trial in Korea.
| · Product : | NEUROSTEM® (human Umbilical Cord Blood-derived Mesenchymal Stem Cells) |
| · Manufacturer : | MEDIPOST Co., Ltd. |
| · Indication : | Treatment of Alzheimer's disease |
| · Route of Administration : | Intra-ventricular administration |
Before and after the administration of NEUROSTEM® (animal experiments)
NEUROSTEM® Mechanism of Action video
The accumulation of β-amyloid in the brain, which causes Alzheimer-type dementia, induces learning and memory disorder by damaging the nerve cells. Once NEUROSTEM® is administrated to the patient’s brain with Alzheimer-type dementia, the umbilical cord blood-derived mesenchymal stem cells migrate towards the injury signals within the damaged brain and secrete proteins which stimulate microglia cells. The stimulated microglia cells promote the degradation of β-amyloid by secreting β-amyloid degrading enzymes.
Mechanism of Action for NEUROSTEM®
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